This study used the fractional B-spline collocation technique to obtain the numerical solution of fractal-fractional differential equations. The technique was considered to solve the fractal-fractional differential equations (FFDEs) with (). In this suggested technique, the B-spline of fractional order was utilised in the collocation technique. The scheme was easily attained, efficient, and relatively precise with reduced computational work numerical findings. Via the proposed technique, FFDEs can be reduced for solving a system of linear algebraic equations using an appropriate numerical approach. The verified numerical illustrative experiments were presented will show the effectiveness of the technique proposed in this study in solving FFDEs in three cases of nonlocal integral and differential operators namely power law kernel, when the kernels are exponential and the generalization of Mittag-Leffler kernel. The approximate solution is very good and accurate to the exact solution.

Digital technologies witnessed rapid advancements in many domains such as computing, programming, cloud computing, data storing, networking, satellite broadcasting, mobile technologies, but increasingly also in the natural sciences, such as medicine, biology, chemistry, pharmacy, etc. These advancements lead to a massive explosion in data volumes which expected to exceed 175ZB (175x1021 Byte) by end of the year 2025. When data size exceeds normal manageable storable sizes, it will be called “big data”. Organizing and analyzing this “big data” with appropriate tools would produce quite valuable results helping decisions and policymakers. Big data also can assist significantly improve the life quality of much of the world’s population. The United Nations, governments, non-profitable and other organizations are utilizing big data to assist achieving the UN’s Sustainable Development Goals (SDG), a set of 17 targets pertinent to protect the natural environment, fighting hunger and poverty, reducing inequality, improving health outcomes and other things that will make life better around the world. Big data analysis could be used in many ways to enhance the understanding of the progress towards the SDGs, specify how best to meet SDGs targets, and ensure accountability. The UN has set up a task team to explore how to use big data to help achieve the SDGs. A survey by the task team found that big data projects most frequently focused on the “no poverty” goal, it was found that mobile phone data was the most common data source.

Abstract:

Nepeta cyrenaica Quézel & Zaffran (Lamiaceae), an endemic species of Libyan flora, is here characterized for the first time for its phytochemical composition and biological activities. Phenolic composition, antioxidant and enzyme inhibiting effects of extracts, prepared from five-week-old in vitro propagated N. cyrenaica shoots, were evaluated. Extraction was performed using dichloromethane, methanol, 96% ethanol or hot distilled water. LC-MS analysis showed that the methanol extract contained the highest amount of phenolic components, especially ferulic and rosmarinic acids (1300.73 mg/kg and 528.88 mg/kg, respectively), and epigallocatechin gallate (719.05 mg/kg). The strongest antioxidant activity was recorded for aqueous extract in DPPH assay (66.91%) and dichloromethane extract in β-carotene bleaching assay (81.06%), both tested at the concentration of 2 mg/mL. Concerning α-glucosidase inhibition, dichloromethane extract was shown to possess a higher inhibition capacity than acarbose at the concentration of 2 mg/mL (95.33% vs. 88.29%). The aqueous extract exhibited higher acetylcholinesterase inhibition than the other tested extracts, which was lower compared to the positive control, galantamine. Although methanol extract contained the highest amount of polyphenolics, dichloromethane and aqueous extracts were shown to be more suitable for the extraction of bioactive components. In conclusion, endemic N. cyrenaica could be efficiently propagated through in vitro propagation protocols as a polyphenolic-rich plant with valuable medicinal potential.

Keywords: biological activities; extracts; in vitro propagation; Nepeta cyrenaica

This study considers the diagenetic processes and the depositional settings of Lower Jurassic gypsum of the Bi'r Elghanem Formation in the northwestern of Libya. The paleo-environment study has revealed a variety of depositional environment ranging from lagoonal to fluvial deposit and evaporitic basins, which become intensely saline as a result of evaporation due to (semi-) arid environments. Samples were analyzed using elemental analysis, statistical evaluation such as Multiple Correlations, Principal Component Analysis, and mineralogical evidence to determine their mode of environmental deposition, mineralogical and geochemical composition. The geochemical results indicate that gypsum has evidence of mineral substitutions and displacement, suggesting a homologous mechanism for lithofacies and subsequent textural change. The development of gypsum minerals in a variety of lithologies and textures is aided by eustatic fluctuations in lake water level due to regional tectonism and climate.

Lithostratigraphically, the Sidi As sid Formation (Upper Cretaceous) in the El Zintan section (JabalNafusah, NW Libya) consists of three units: upper marl, middle marl with intercalations of dolostone, and lower dolostone. Based on crystal size and shape, three types of dolomite have been classified. Fine crystalline dolomite (D1) consists of nonplanar dolomites, fine to medium crystalline dolomite (D2), and very coarse, consisting of mostly planar dolomites (D-3). The Cathodoluminescence technique also showed that most of these dolomites have bright yellow to red and dull orange luminescence and zoning. Based on X-ray diffraction (XRD), all dolomites are relatively well ordered and non to nearly stoichiometric dolomite. The stable isotopic studies and element analysis show that the major elements such as sodium (D1: 412.166 ppm; D2: 175 ppm; D3: 420 ppm), strontium (D1: 107 ppm; D2: 85 ppm; D3: 81.2 ppm), manganese (D1: 271 ppm; D2: 91 ppm; V3: 242 ppm), and iron (D1: 4856.66 ppm; D2: 373 ppm; D3: 3287 ppm) and the values of the stable isotope of oxygen (D1:-2.202‰; D2:-2.131; D3:-4.359‰) and carbon (D1: 2.080; D2: 2.076‰; D3: 1.581‰). The values of major elements and depletion of the carbon and oxygen isotopes can be related to the effects of temperature diagenetic, and mesosaline reflux of dolomitizing fluids during the early diagenesis. These dolomites originated in a tidal environment in this Formation. The major sources of magnesium for the dolomites are seawater and hypersaline fluids.